Pharmacology: notes and exam prep for MU Sofia

General pharmacology16 topics

1. 1Object and branches of pharmacology. Connection with other sciences. Historical review. Sources of drugs.free
2. 2Drug - definition, origin, nomenclature. Drug form and drug product - definition. Drug preparations.free
3. 3Drug development - stages and phases.free
4. 4Transmembrane transport of drugs.free
5. 5Drug absorption after various routes of administration.free
6. 6Drug distribution.free
7. 7Drug metabolism.free
8. 8Drug excretion.free
9. 9Specific and non-specific types of drug action. Types of receptors.free
10. 10Characteristics of the receptor action of the drugs.free
11. 11Drug properties and environmental factors affecting drug pharmacokinetics and drug pharmacodynamics.free
12. 12Factors from the human body affecting the drug pharmacokinetics and drug pharmacodynamics.free
13. 13Effects occurring after repeated drug administration.free
14. 14Drug interactions at a pharmacokinetic level.free
15. 15Drug interactions at a pharmacodynamic level.free
16. 16Pharmaceutical drug interactions (drug incompatibility). Drugs affecting clinical laboratory tests. Interactions of drugs with foods.free

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Pharmacology of organ systems68 topics

1. 17Pharmacological modulation of the cholinergic neurotransmission - levels and mechanisms.
2. 18Cholinergic drugs (cholinomimetics).
3. 19Antimuscarinic drugs (M-cholinolytics).
4. 20Neuromuscular blockers (Peripheral muscle relaxants).
5. 21Pharmacological modulation of the adrenergic neurotransmission - levels and mechanisms.
6. 22Adrenomimetics.
7. 23Alpha-adrenergic blocking agents. Agonists of the central presynaptic α2a-adrenergic receptors.
8. 24Beta-adrenergic blocking agents.
9. 25Histamine antagonists.
10. 26Serotonin agonists and antiserotoninergic drugs.
11. 27Local anaesthetics.
12. 28General anaesthetics.
13. 29Hypnotics. Sedative drugs with plant origin.
14. 30Antiepileptic drugs.
15. 31Antiparkinsonian drugs.
16. 32Neuroleptics.
17. 33Anxiolytics. Muscle relaxants with central action.
18. 34Antidepressants. Antimanic drugs.
19. 35Psychostimulants. Nootropic drugs.
20. 36Opioid analgesics.
21. 37Nonsteroidal anti-inflammatory drugs. Non-opioid analgesics.
22. 38Antirheumatoid drugs.
23. 39Antigout drugs.
24. 40Calcium channel blockers.
25. 41Drugs that affect the renin-angiotensin-aldosterone system.
26. 42Antihypertensive drugs.
27. 43Antiarrhythmic drugs.
28. 44Antianginal (antistenocardial) drugs.
29. 45Drugs for the treatment of heart failure.
30. 46Diuretics.
31. 47Peripheral vasodilators. Pulmonary vasodilatators.
32. 48Antimigraine drugs.
33. 49Antidyslipidemic drugs.
34. 50Haematopoietic drugs.
35. 51Haemostatics (antihemorrhagic) drugs.
36. 52Anticoagulants.
37. 53Fibrinolytics. Antiplatelet drugs.
38. 54Antiasthmatic and antitusive drugs.
39. 55Antiulcer drugs.
40. 56Antiemetic drugs.
41. 57Hepatoprotectors. Drugs that affect bile secretion. Pancreatic enzyme preparations.
42. 58Laxative drugs.
43. 59Antidiarrheal drugs.
44. 60Drugs that affect calcium and phosphorus exchange. Antigout drugs.
45. 61Hypothalamic and pituitary hormones - drugs and clinical application.
46. 62Thyreoactive drugs.
47. 63Insulins and insulin analogues.
48. 64Oral antidiabetic drugs.
49. 65Glucocorticoids and mineralcorticoids.
50. 66Drugs affecting bone mineral homeostasis. Antiosteoporotic drugs
51. 67Female sex hormones - drugs and clinical application. Hormonal contraceptives. Uteroactive drugs.
52. 68Male sex hormones - drugs and clinical application. Anabolic drugs. Drugs for the treatment of erectile dysfunction.
53. 69Antibiotics - classification; mechanisms, type of action.and antimicrobial spectrum. Principles of the rational antibiotic therapy and prophylaxis.
54. 70Penicillins.
55. 71Cephalosporins.
56. 72Carbapenems and monobactams. Glycopeptides. Fosfomycin.
57. 73Drugs affecting the 30S protein synthesis of bacteria - aminoglycosides, tetracyclines.
58. 74Drugs affecting the 50S protein synthesis of bacteria - macrolides, lincosamides, amphenicols, etc.
59. 75Drugs affecting folate synthesis and nucleic acids of bacteria - sulfonamides, quinolones, etc.
60. 76Antituberculosis drugs. Antileprosy drugs.
61. 77Antimycotics.
62. 78Antiviral drugs.
63. 79Antiprotozoal drugs.
64. 80Antihelmintic drugs.
65. 81Antiseptics and disinfectants.
66. 82Antitumor chemotherapeuticals.
67. 83Hormonal antitumor drugs. Target antitumor drugs.
68. 84Immunomodulators.

Drug toxicology7 topics

1. 85Side effects of drugs.free
2. 86Organ toxic effects of drugs.free
3. 87Fetal damage caused by drugs.free
4. 88Principles of treatment of acute drug poisoning.
5. 89Antidotes.
6. 90Acute intoxication and abuse of opioids. Principles of the treatment.
7. 91Acute intoxication and abuse of benzodiazepines. Principles of the treatment.